microcephalic (mc) gene
| mc = microcephalic |
|
Gene:
|
mc
|
|
Feature/structure:
|
Eyes and head
|
|
Linkage Group:
|
5
|
|
Origin:
|
spontaneous [from Sokoloff]
|
|
Description:
|
• Width of head is reduced posterior to genal shelf.
• Eyes are variably reduced, ranging from slight reduction in eye size and number of facets, to complete reduction with no facets. Not bilaterally uniform.
• One strain occasionally has an "eye-growth" which appears on a sclerotized encroachment into the anterior edge of the eye. The growth ranges from very small and fine, and often appears segmented in its largest and strongest expression.
|
|
Illustration:
|
|
| |
| T(2;5) mc(Ey) = microcephalic(Eyeless) |
|
Gene:
|
mc
|
|
Feature/structure:
|
Eyes and head
|
|
Linkage Group:
|
( 2 ,
5 )
|
|
Origin:
|
Gamma irradiatin of GA-1 [wild-type].
|
|
Description:
|
• Dominant allele of mc on LG 5, with a similar range of expression [see mc]. Ey is a T[2;5].
• The lethality seems to be associated with LG 2, since Dp[2]/Ey/Ey is viable [where Dp is derived from mxpDch/Es1].
• Ey is a good HOM-C balancer, [good crossover suppression, fertile, fully penetrant, heterozygotes extremely viable, homozygous lethal]. Only one recombinant [out of ca. 2000] has been observed, placing Ey closer to the mxp-apt region than to the A region.
|
| |
|
