Dr. Marcé Lorenzen Biological Research Unit Grain Marketing & Production Research Center   1515 College Ave. Manhattan, KS 66502 Voice: (785) 313-0712 Fax: (785) 537-5584 marce@ksu.edu

Research Interests

Marcé Lorenzen is an Adjunct Assistant Professor in the Department of Entomology at Kansas State University. She received a B.S. in Zoology from the University of Rhode Island in 1994 and her Ph.D. in Molecular Genetics from Kansas State University in 2000. She has studied the genetics and genomics of the red flour beetle, Tribolium castaneum, for over 15 years in an effort to develop better, safer, more effective ways to control agricultural pests. Currently she is collaborating with Drs. Richard Beeman (USDA) and Yoonseong Park (KSU) to elucidate the molecular mechanism that underlies a class of novel selfish-genetic element found only in Tribolium. Due to the selfish behavior of these elements they have potential as gene "drivers" to push pesticide susceptibility into populations of insect pests of crops, or vector incompetence into populations of insect vectors of disease.

Magazine Articles

Beetle Mania

News, Miscellaneous

Agricultural Pest's Genome is Sequenced

Key Red Flour Beetle Gene Sequenced

Selected Publications

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	Publications	Check Out
PDF	Lorenzen, M.D., A. Gnirke, J. Margolis, J. Garnes, M. Campbell, J.J. Stuart, R. Aggarwal, S. Richards, Y. Park, and R.W. Beeman. 2008. The maternal-effect, selfish genetic element Medea is associated with a composite Tc1 transposon. Proc. Natl. Acad. Sci. USA 105: 10085-10089.
PDF	Park, Y., J. Aikins, L.J. Wang, R.W. Beeman, B. Oppert, J.C. Lord, S.J. Brown, M.D. Lorenzen, S. Richards, G.M. Weinstock, and R.A. Gibbs. 2008. Analysis of transcriptome data in the red flour beetle, Tribolium castaneum. Insect Biochem. Mol. Biol. 38: 380-386.
PDF	Siebert, K.S., M.D. Lorenzen, S.J. Brown, Y. Park, and R.W. Beeman. 2008. Tubulin superfamily genes in Tribolium castaneum and the use of a tubulin promoter to drive transgene expression. Insect Biochem. Mol. Biol. 38: 749-755.
PDF	Tribolium Sequencing Consortium (includes R.W. Beeman, M.D. Lorenzen, B. Oppert, J. Lord, K. Kramer, Y. Arakane). 2008. The genome of the model beetle and pest Tribolium castaneum. Nature 452: 949-955.
PDF	Wang, S., M.D. Lorenzen, R.W. Beeman, and S.J. Brown. 2008. Analysis of repetitive DNA distribution patterns in the Tribolium castaneum genome. Genome Biol. 9: R61.
PDF	Lorenzen, M.D., T. Kimzey, T.D. Shippy, S.J. Brown, R.E. Denell, and R.W. Beeman. 2007. piggyBac-based insertional mutagenesis in Tribolium castaneum using donor/helper hybrids. Insect Mol. Biol. 16: 265-275.
PDF	Weinstock, G.M. ... Lorenzen, M.D. …. 2006. Insights into social insects from the genome of the honeybee Apis mellifera. Nature 443: 931-959.
PDF	Arakane, Y., S. Muthukrishnan, K.J. Kramer, C.A. Specht, Y. Tomoyasu, M.D. Lorenzen, M. Kanost, and R.W. Beeman. 2005. The Tribolium chitin synthase genes TcCHS1 and TcCHS2 are specialized for synthesis of epidermal cuticle and midgut peritrophic matrix. Insect Mol. Biol. 14: 453-463.
PDF	Lorenzen, M.D., Z. Doyungan, J. Savard, K. Snow, L.R. Crumly, T.D. Shippy, J.J. Stuart, S.J. Brown, and R.W. Beeman. 2005. Genetic linkage maps of the red flour beetle, Tribolium castaneum, based on bacterial artificial chromosomes and expressed sequence tags. Genetics 170: 741-747.
PDF	Goodwin, T.J.D., R.T.M. Poulter, M.D. Lorenzen, and R.W. Beeman. 2004. DIRS retroelements in arthropods: identification of the recently active TcDirs1 element in the red flour beetle Tribolium castaneum. Mol. Genet. Genom. 272: 47-56.
PDF	Lorenzen, M.D., A.J. Berghammer, S.J. Brown, R.E. Denell, M. Klingler, and R.W. Beeman. 2003. piggyBac-mediated germline transformation in the beetle Tribolium castaneum. Insect Mol. Biol. 12: 433-440.
PDF	Lorenzen, M.D., S.J. Brown, R.E. Denell, and R.W. Beeman. 2002. Cloning and characterization of the Tribolium castaneum eye-color genes encoding tryptophan oxygenase and kynurenine 3-monooxygenase. Genetics 160: 225-234.
PDF	Lorenzen, M.D., S.J. Brown, R.E. Denell, and R.W. Beeman. 2002. Transgene expression from the Tribolium castaneum Polyubiquitin promoter. Insect Mol. Biol. 11: 399-407.
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